This function computes population specific Fst, using the approach in Weir
and Goudet 2017 (as computed by hierfstat::fst.dosage()
).
Arguments
- .x
a grouped
gen_tibble
(as obtained by usingdplyr::group_by()
)- include_global
boolean determining whether, besides the population specific Fst, a global Fst should be appended. Note that this will return a vector of n populations plus 1 (the global value)
- allele_sharing_mat
optional, the matrix of Allele Sharing returned by
pairwise_allele_sharing()
withas_matrix=TRUE
. As a number of statistics can be derived from the Allele Sharing matrix,
References
Weir, BS and Goudet J (2017) A Unified Characterization of Population Structure and Relatedness. Genetics (2017) 206:2085
Examples
example_gt <- example_gt("grouped_gen_tbl")
# Compute FIS using Nei87
example_gt %>% pop_fst()
#> pop1 pop2 pop3
#> 0.05246079 0.06544078 0.41590049
# To include the global Fst, set include_global = TRUE
example_gt %>% pop_fst(include_global = TRUE)
#> pop1 pop2 pop3 global
#> 0.05246079 0.06544078 0.41590049 0.17793402
# To calculate from a pre-computed allele sharing matrix:
allele_sharing_mat <- pairwise_allele_sharing(example_gt, as_matrix = TRUE)
example_gt %>% pop_fst(allele_sharing_mat = allele_sharing_mat)
#> pop1 pop2 pop3
#> 0.05246079 0.06544078 0.41590049